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By 48 weeks, weight loss reached 14.0% with the 6 mg dose, with 49.5% achieving at least 15% loss versus 2.0% with placebo

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The NP to fibrosis ratio in post-PELD tissues was calculated to be 0.354 0 0.036 8, further confirming that the IVDs from patients who underwent PELD were more fibrotic than normal IVDs (Fig