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There are very few side effects from growth hormone releasing hormones / peptides and IGF-1/IGF LR3

Cellular senescence is dynamic, often compromising normal tissue functionality by continuously secreting pro-inflammatory cytokines, chemokines, growth factors, and matrix metalloproteinasescollectively termed senescence-associated secretory phenotype (SASP) factors

Reduction of insulin/IGF-1 receptor rejuvenates immunity via positive feedback circuit

Dopamine is involved in motivation, reward, focus, and movement, while serotonin regulates mood, sleep, appetite, and emotional balance