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Studied in models involving methylation cycle activity, homocysteine metabolism, and cellular biochemical pathways

Trevaskis JL, Wittmer C, Athanacio J, Griffin PS, Parkes DG, Roth JD

The search for this elusive substance ended in 1932 when Albert Szent-GyorgyiExit Disclaimer, a Hungarian biochemist, isolated and identified a 6-carbon carbohydrate, hexuronic acid, as the anti-scurvy factor

Materials and methods 2.1

Silymarin and caffeine combination ameliorates experimentally-induced hepatic fibrosis through down-regulation of LPAR1 expression