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In canonical Wnt/-catenin signaling, the secreted Wnt ligands bind with the Frizzled receptor, which further inactivates glycogen synthase kinase-3 (GSK-3), which is an enzyme responsible for the ubiquitination-mediated degradation of -catenin 4,5

Bioinformatics study of the potential therapeutic effects of ginsenoside rf in reversing nonalcoholic fatty liver disease

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doi: 10.1016/0024-3205(92)90504-i