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Lan G, Wang P, Chan RB, Liu Z, Yu Z, Liu X et al

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These metabolic effects highlight the need for careful monitoring during prolonged use, he explains

Add 16 to 24 ounces for each hour of moderate exercise, hot weather exposure, or significant fluid loss

Apperloo EM, Neuen BL, Fletcher RA, et al

Fatty food slows stomach emptying and that can make nausea and GI issues worse, Dr