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Conclusion GLP-1 receptor agonists represent a significant advancement in managing pediatric diabetes and obesity, providing options that directly address insulin resistance, promote weight loss and reduce risks from related comorbidities

3.4 Appetite regulation and weight management Similar to animal studies with deletion of the GIPR gene that exhibit protection toward obesity (53), early genome-wide association studies (GWAS) in humans have revealed the GIPR gene to be associated with BMI (103)

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