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In addition to their structural functions, N-3 PUFA exert anti-inflammatory properties through activation of Peroxisome proliferator-activated receptor gamma (PPAR-), contributing to the downregulation of NF-B-induced cytokine production (e.g., TNF-, IL-6) 34,35,36 , and the upregulation of microglial phagocytosis of A aggregates 37

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[DOI] [PMC free article] [PubMed] [Google Scholar] 80.Reger M.A., Watson G.S., Green P.S., Baker L.D., Cholerton B., Fishel M.A., Plymate S.R., Cherrier M.M., Schellenberg G.D., Ii W.H.F., et al

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