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Lipid-based formulations for oral administration of poorly water-soluble drugs

White WB, Cannon CP, Heller SR, Nissen SE, Bergenstal RM, Bakris GL, Perez AT, Fleck PR, Mehta CR, Kupfer S, et al

Plasma preparation was carried out as described previously 47

Weight regain is common in various weight-loss strategies and it is necessary to establish long-term anti-obesity treatment in clinical practice, the researchers said

Hepatic glutathione stores are prioritised over systemic circulation, meaning only 1015% of an oral dose reaches peripheral tissues where oxidative stress from lipolysis is highest

& Bugianesi, E