Appetite suppression, though often listed as a side effect, is actually the intended therapeutic mechanism
In a landmark study by Shain et al, some important conclusions were reached
Kumaran S, Panneerselvam KS, Shila S, Sivarajan K, Panneerselvam C: Age-associated deficit of mitochondrial oxidative phosphorylation in skeletal muscle: role of carnitine and lipoic acid
Semaglutide, a GLP-1 receptor agonist, reaches steady-state blood levels after four to five weeks of once-weekly dosing, with a half-life of approximately one week
In the end I was too vain to keep hoping and went back to cyanocobalamin, which has never affected my skin
If more than 5 days have passed, skip the missed dose and resume your regular weekly schedule on your next scheduled day