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Use of AI tools: Artificial Intelligence (AI) assistance (GPT-5, OpenAI) was used only for improving the English language, grammar, and phrasing of the manuscript

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Mechanism of Action Nitric Oxide Synthase Pathway : L-citrulline works by converting to arginine through the urea cycle via argininosuccinate synthase and argininosuccinate lyase enzymes, then interacting with nitric oxide synthase (NOS) enzymes to generate nitric oxide and support the relaxation of blood vessel smooth muscle