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Single site mutations at asparagine residues were shown to result in a functionally active yet slightly less thermally stable version of the enzyme in vitro, while knockout of all asparagine residues resulted in an accumulation of the uncleaved, propeptide form of the enzyme

Nature Reviews Disease Primers

For short-term use (ranging from a few days to several weeks), refrigeration below 4C (39F) is suitable

Dizziness: Occasionally reported, possibly related to blood pressure effects

Chandler, P

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