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Carotenoids may upregulate the activity of antioxidant enzymes, mainly via the activation of the Nuclear factor erythroid 2-related factor 2 (Nrf2)-dependent pathway (Kaulmann and Bohn 2014)

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More recently, the contributions of Fc-dependent effector functions to the antiviral activity of nAbs have been explored using antibodies engineered to have point substitutions in the Fc region that reduce, eliminate or enhance such functions 116,117,118

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