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The authors identified BPC-157 as having significant potential for conservative treatment of hypovascular and hypocellular soft tissues such as tendon and ligaments and reported adverse reactions as minimal across all available studies

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The pathophysiological mechanisms underlying these impairments involve an altered follicular environment characterized by increased inflammation and oxidative stress

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In a mouse model of shoulder arthrofibrosis, multiple intraarticular injections of human relaxin-2 restored range of motion and eliminated capsular fibrosis