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This is most helpful when the patient experiences specific triggers or if the symptoms tend to occur daily, in which case a 24-hour Holter monitor can be ordered

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Total N = 6 750, sample size per each cohort/ancestry can be found in Table 1

endothelial, plasma, tissue) and are commonly used in the literature to assess the amount of oxidative stress that is occurring

During purine degradation, xanthine oxidase located in cytosol and peroxisomes catalysed the hydroxylation reaction of hypoxanthine and xanthine molecules to produce H 2 O 2 and other oxygen radicals

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