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Cholestyramine, a bile salt resin, effectively alleviates cholestatic pruritus and is the first-line treatment even in cirrhosis due to its general tolerability and safety (4)

Guex, N

Cell Stem Cell 30(5):512-529

Intriguingly, UA level will restore at higher concentrations of losartan mainly due to trans-stimulation of these ARBs at higher concentrations (Iwanaga et al., 2007)