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A., Borzutzky, A., Damsgaard, C
Its accumulation causes the swelling of astrocytes during hyperammonemia (Alzheimer type II astrocyte) [2]
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In addition, NRF2-addicted cells exhibit further elevated expression of SLC7A11 , GCLC, and GCLM due to additional cooperative input to the NRF2-mediated transcriptional activation
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Since both drugs activate the GLP-1 receptor, patients with less favorable variants in this gene may have a biological ceiling that limits response to the entire class
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