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When used in conjunction with diet and exercise, it can cause significant weight loss, and possibly reduce risk of cancer, diabetes and heart disease in people who are overweight

Be prepared for the possibility of contesting a denial, as persistence may be necessary to secure support

Avoid injecting right before important events or busy workdays, especially during dose escalation weeks when side effects are stronger

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Tirzepatide is administered as a once-weekly subcutaneous injection, with doses typically starting at 2.5 mg and gradually increasing by 2.5 mg every 4 weeks as tolerated to a maintenance dose ranging from 5 mg to 15 mg, depending on individual response and tolerability

[7] Monitoring kidney function is especially important in older adults or those with preexisting kidney disease