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The present study aimed to develop and validate a conversion SIDA method that determines total B12 as CNCbl after cyanidation conversion and to further compare the developed method with a previously developed multi-SIDA method targeting individual native vitamers (hereafter referred as native SIDA method)

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It is naturally produced in the body, but its level gets depleted with age and environmental stressors

A 1980 paper in Nature proposed that GHK functions by facilitating copper uptake into cells [4]

2 Materials and methods 2.1 Chemicals and reagents Protease and phosphatase inhibitors and Bradford Protein Assay Kit were purchased from Beyotime (Haimen, China)

The influence of CYPs in this context was confirmed by a study comparing the administration of LCP-Tac and IR-Tac in African Americans and showing that PK was significantly less affected in the case of LCP-Tac than IR-Tac (118)