Symptoms of vitamin B-12 deficiency include: Fatigue Difficulty concentrating Decreased mood Loss of appetite Poor memory Constipation Higher-risk groups for vitamin B-12 deficiency include people with intestinal disorders such as Crohns or Celiac disease, as well as those who suffer from muscular degeneration, Lou Gehrigs disease or diabetes
Psychiatry 10 , 329332 (2005)
Indeed, decreased serotonin levels have been reported in HIV (Peltenburg et al., 2018) and TB (Cho et al., 2020) patients
Physiological functions of thioredoxin and thioredoxin reductase
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