To establish the T2DM model, after 8 weeks of HFD (10% lard, 20% sucrose, 2.5% cholesterol, 1% bile salt, and 66.5% regular diet), rats received the intraperitoneal (i.p.) injection of 35 mg/kg STZ (Sigma) after overnight fasting
Both these strategies are found to be successful in overcoming deficiencies of endogenous GLP-1 or providing supra-physiological levels of GLP-1
Looking ahead, new treatment options and growing experience among healthcare providers may help improve access and affordability
The emerging data on GLP-1 receptor agonists and neurodegeneration adds another dimension
So it turns out these hormones are just key physiologic signals
Dinner options that work: ribeye steak with roasted broccoli in olive oil, chicken thighs cooked in coconut oil with a side of cauliflower mash, pork chops with a large green salad dressed with high-fat dressing, or a keto-friendly casserole built around meat and cheese