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Preclinical and early-phase clinical investigations have examined its impact on body weight and fat mass: In obese animal models, AOD9604 has been associated with reductions in body weight and fat mass over defined treatment periods

These newly synthesized analogs possess a molecular structure similar to anthranilic acid analogs that inhibit COX

Plasma Nitrate Levels Are Related to Metabolic Syndrome and Are Not Altered by Treatment with DPP-4 Inhibitor Linagliptin: A Randomised, Placebo-Controlled Trial in Patients with Early Type 2 Diabetes Mellitus

But this molecular activity doesn't translate to visible or measurable changes yet

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