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GLP1RAs have shown broad cardiometabolic benefits

Compared with other CVOTs involving GLP-1RA, participants in the AMPLITUDE-O trial had the longest duration of diabetes (15 years), lowest mean eGFR (72 ml/min/1.73 m 2 ) with a higher percentage (32%) of people with renal disease (eGFR 2560 mL/min), highest glycosilated hemoglobin (8.9%), and highest percentage of insulin use (62%) or sodiumglucose transporter-2 inhibitors (SGLT-2i) (15%) at baseline, thus identifying a more fragile population

10.1038/nature13148 95 MaoC.LiuX.ZhangY.LeiG.YanY.LeeH.et al (2021)

Your provider will monitor you to make sure youre not experiencing any allergic reactions or adverse side effects during your treatment

BMJ Open 9(5):e024065

Frontiers in Pharmacology, 2017: 904