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Certain enteric pathogens possess mechanisms that enable their direct adherence to IECS while others permit the secretion of effector proteins or enterotoxins via membrane localised secretion systems that typically target TJs thereby increasing intestinal permeability by disrupting the intracellular cytoskeleton of IECs (Knig et al

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Eur J Biochem 261: 405412

To ensure your safety, it is best to avoid drinking alcohol for at least 24 hours after taking acetaminophen