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Gastrointestinal side effects represent the most commonly reported adverse reactions associated with this medication, primarily due to the semaglutide components effects on gastric emptying and gastrointestinal motility

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Nevertheless, the precise cell types contributing DPP-4 to the pool targeted pharmacologically by DPP4i remains incompletely understood and may depend on the experimental model and pharmacodynamic endpoint(s) under investigation

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Changes in cognitive function, body mass index (BMI), blood glucose level, and insulin content were analyzed