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Similar content being viewed by others 1 Introduction Semaglutide (US brand name Ozempic or Wegovy), a Glucagon-like peptide-1 receptor (GLP-1R) agonist containing the active ingredient semaglutide, is approved by the Food and Drug Administration for its potential therapeutic role in obesity and diabetes mellitus (DM) similar to other agonists within the GLP-1R family such as liraglutide

Semaglutide is well-tolerated in clinical practice when dosed appropriately

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Discontinuing semaglutide after weight loss: strategy for weight maintenance and a possible new side effect

While these findings were reassuring, there were other findings of note

In a subgroup of 98 participants with nonalcoholic fatty liver disease in the trial, 90% of participants in the highest dose of retaglutide group had normalized liver fat content