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Data availability Computer code for LSA, parameter estimation, numerical simulations, and GSA with PRCC was implemented in and run with the programming and computation software MATLAB (MathWorks Inc., Natick, MA, USA)

The retatrutide reconstitution chart uses the same 10 mg/mL concentration target

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In contrast, glutamate and GABA can produce fast responses by directly opening ion channels and can produce slow responses by activating receptors coupled to G-proteins