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In trials, diarrhoea was often transient, occurring in the early weeks

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Frhbeck G, Toplak H, Woodward E, Yumuk V, Maislos M, Oppert J-M

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Because ethanol metabolism by ADH and ALDH occurs essentially only in the liver, any of the adverse effects described above that are associated with ethanol metabolism by these enzymes, and the associated ROS production, primarily affect that organ

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