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B.JuneC

(2020) 105:e2695e709

GLP-1 Analog Liraglutide Protects Against Cardiac Steatosis, Oxidative Stress and Apoptosis in Streptozotocin-Induced Diabetic Rats

The use of advanced techniques, such as computational mutagenesis, has been instrumental in identifying mutations that affect protein stability, which is crucial for understanding the underlying genetic causes of the deficiency

It has also been used successfully for the treatment of acute respiratory distress syndrome at a dose of 150mg/kg on day one followed by 50mg/kg for 3 days, with efficacy in part determined by GST polymorphisms

In addition, a high-resolution cryo-EM analysis (at better than 2.0 resolution) is presented for CP17 bound to a VLP of wild-type (wt) PV2