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In a more extensive way, we should note that a purposive movement requires the impulses passing from the motor cortex via the spinal cord to the appropriate muscles and the movement pattern coordinated by the impulses passing through various parts of the brain and sending messages back to the motor cortex [8]

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Through its interaction with CAan enzyme essential for maintaining the carbon dioxidebicarbonate balance and physiological pHPolmacoxib may modulate COX-2 inhibition in cardiovascular tissues where both pathways coexist

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