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Anticancer activity of oleanolic acid and its derivatives: Recent advances in evidence, target profiling and mechanisms of action

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Although several clinical trials have been completed or are ongoing, scientific understanding continues to evolve

12885_2025_13546_MOESM2_ESM.tif (download TIF Supplementary Material 2: Supplementary Fig

Another natural compound, trigonelline, a methylated form of nicotinic acid, is a newly discovered NAD + precursor able to increase NAD + in multiple species, with preclinical implications for use in sarcopenia, and for muscle and cognitive decline in aging 124,130,131