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Dosing began at 0.25 mg of each active drug and escalated every four weeks until the full 2.4 mg dose was reached by week 16

Vondriska, Enrico Stefani & Arjun Deb, "

# 1072510100) diluted in endotoxin-free phosphate-buffered saline (PBS) with an injection volume of 100 L/20 g body weight

Crit Rev Biochem Mol Biol 30:521600

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In our study, melatonin-treated ILC2s exhibited increased intracellular NRF2 staining, consistent with enhanced availability of active NRF2