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In Europe, the European Medicines Agency supports two main regulatory tracks: well-established use and traditional use registration under Directive 2004/24/EC, which requires data on safety, efficacy, and pharmacovigilance

were currently engineering variants of the FXII inhibitor with a longer retention time. Funding Swiss National Science Foundation NCCR Chemical Biology Marie Skodowska-Curie individual fellowship References Jonas Wilbs, Xu-Dong Kong, Simon J

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doi: 10.1371/journal.pntd.0002701 97 HuangP

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