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Ferroptotic injury promotes the release of pro-inflammatory mediators and amplifies oxidative stress ( Downstream of HIFiron remodeling, ferroptosis in intestinal epithelial cells (IECs) constitutes a key mechanism that converts upstream threshold shifts into epithelial barrier failure and inflammatory amplification in IBD

The men in the study also reported improvements in their overall quality of life, including increased energy levels and a reduction in anxiety and depression

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