Myth #12: Everyone Who Loses Weight Ends Up Worse Than Before The Claim: People lose weight then regain it all plus extra, ending up heavier and more metabolically damaged than when they started (Reddit r/antidiet post) The Reality: Weight cycling is concerning, but medication-assisted weight loss followed by maintenance (either through continued medication or lifestyle) doesnt lead to worse outcomes than never losing weight
Which is why Biotin deficiency can cause dry skin, brittle nails and hair and even hair loss, acne and psoriasis
And theres enough evidence that we do other type of interventions, which are far more risky and unknown outcomes, and we are able to pay for them appropriately and have patients have access to them
Moreover, knockdown of BRCA1 sensitized CCNE1-driven cells to DNA-damaging agents to a similar extent as the inhibition of IDH1 or de novo carnitine synthesis using mildronate (Extended Data Fig
Cell Metabolism , 27(6), 1212-1221
Garg advises
