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Major Findings: Significantly reduced liver fat content

As of July 31, 2025, the FDA has received: Some of these reports involve serious reactions such as nausea, vomiting, abdominal pain, constipation, and dosing errors, especially when patients or providers miscalculate injections or exceed FDA-approved dosing schedules

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These results further support the notion that CYP8B1 is regulated by T3, which requires hepatic TR

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Other recognised effects include injection site reactions, and rarely, acute pancreatitis, gallbladder disease, or diabetic retinopathy complications with rapid glucose improvement