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Folinic acid may be appropriate when folate receptor antibodies interfere with cerebral folate transport, but that question is different from simply finding an MTHFR variant

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The GCL enzyme is a heterodimer formed by two subunits: the heavy subunit or glutamate cysteine ligase catalytic subunit (GCLC, 73 kDa) and the light subunit or glutamate cysteine ligase modulating subunit (GCLM, 30 kDa)

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The substantial upregulation of FAP is considered a biomarker for CAFs [33, 34], with potential as a unfavourable prognosis biomarker for various cancers [35,36,37,38]

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