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Tachyphylaxis and Duration of Effects A key feature of gastric effects associated with GLP-1 RA is the phenomenon of tachyphylaxis, where the gastric emptying effects diminish over time with continuous exposure lasting 8 to 24 h [18]

This does not mean the injection was done incorrectly

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2 Stifel, Obesity drug review, market update July 1st, 2023, 3 Goldman Sachs Research