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We recommend that patients take these medications only for their approved indications and under the strict supervision of a healthcare professional, who can also advise on potential side effects

Growth Hormone and Sex Steroid Administration in Healthy Aged Women and Men: A Randomized Controlled Trial

Weight gain is also of concern in diabetes patients

Cardiovascular & Renal Benefits of GLP-1 Receptor Agonists Meta-analysis (2024) comprehensive review showing GLP-1RAs reduce major adverse cardiovascular events (MACE), all-cause mortality, stroke, and kidney-related outcomes, in patients with and without diabetes

However, not all patients respond well to these drugs, and some may experience side effects that make it difficult to continue treatment

J Mol Neurosci 68:389396