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Compared to healthy controls, SCD patients have significantly lower erythrocyte GSH and cysteine concentrations 12 and a faster rate of GSH synthesis, suggesting that the endogenous cysteine supply is insufficient to meet all anabolic demands

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The underlying mechanism of this impaired engulfment is linked to the disruption of the Rho GTPase signaling, which is crucial for phagocytosis by pyocyanin-generated ROS (108, 136)

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Collateral pial circulation relates to the degree of brain edema on CT 24 hours after ischemic stroke