JACC Basic Transl Sci 2016;1:267-76.PubMedPMC 25
The Problem Nobody Talks About The headlines scream miracle weight-loss injections. Ozempic, Wegovy, Mounjaroyouve seen them everywhere
Statistical analysis We used cumulative incidences and cause specific hazard regression to estimate hazard ratios (HR) and 95% confidence intervals (CI) for risk of suicide and suicide attempts in GLP-1 RA users vs SGLT-2 inhibitor users or DPP-4 inhibitor users, taking death as a competing risk to suicide into account
This matters when discussing GLP-1 and GIP/GLP-1 medications
(20:21): And we now have a really large phase three study ongoing, but of course, it's a hypothesis, right
For people with T2D, a phase 2 trial showed that 12 weeks of efinopegdutide achieve up to 7.9% WL (compared to 0.7% WL with placebo) without actual improvement in HbA1c [78]