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Did You Know: Some experienced users report that injuries less than one month old often show noticeable improvement within the first week, while chronic injuries extending over a year may require the full 8-week protocol before significant changes occur

Others wait until the patient reports either reduced efficacy or increased side effects

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Rimonabant, the first selective central cannabinoid (CB1) receptor antagonist, was not approved by the FDA because of concerns regarding psychiatric adverse events including depression, anxiety and suicidal ideation [20]

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