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The 4mg dose is often where researchers consider microdosing because the side effect jump from 2mg is significant

First Patient Dose Delivered for Lilly's Tirzepatide Cardiovascular Outcomes Trial INDIANAPOLIS, June 9, 2020 /PRNewswire/ -- The first patient dose has been delivered in SURPASS-CVOT, the phase 3 cardiovascular outcomes trial for tirzepatide, Eli Lilly and Company's (NYSE: LLY) investigational dual GIP and GLP-1 receptor agonist

This is common because semaglutide treatment usually starts at a low dose

Mol Metab 2:468479

Ever notice how your pee changes color, like how it can go from light to super bright yellow after you pop a vitamin B2

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