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Structurally, semaglutide is similar to liraglutide but with two key modifications - replacement of glycine at position 8 with alpha-aminoisobutyric acid and optimization of the fatty acid chain for albumin binding

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Since this compound is not generally used in countries other than Japan, there is a paucity of reports investigating its effects

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Uric acid excretion-promoting drugs, with benzbromarone as the core agent, reduce uric acid reabsorption by inhibiting the URAT1 transporter in the renal tubules

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