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Below curcumin, a linear pathway of metabolism is shown where curcumin is reduced to dihydrocurcumin, then to tetrahydrocurcumin

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Clinical trials show substantial weight loss, especially when combined with semaglutide

The STEP 1 trial recently demonstrated the efficacy of once weekly semaglutide 2.4 mg in adults who are overweight or with obesity, showing a 14.9% reduction in body weight in the treated group compared to 2.4% in the placebo group [9]