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Muscular oxygen supply : may increase oxygen flow to muscles

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Interestingly, GLP-1R V229A also presented with a higher tendency to segregate to cholesterol- and sphingolipid-rich flotillin-positive lipid nanodomains, or lipid rafts, in the apo-state, so that the increased clustering of GLP-1R V229A could potentially be triggered by increased mutant receptor partitioning to these lipid nanodomains

semaglutide is a GLP-1 incretin peptide studied for appetite and insulin effects

Rogers, A., De Paoli, G., Subbarayan, S., Copland, R., Harwood, K., Coyle, J., et al

Nature 480 , 9498 (2011)