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It may not have been dosed correctly." 'Losing 8 litres of fluid a day' on retatrutide Dr Holt, a gastroenterologist who focuses on the digestive system, including the stomach, intestines and liver, treated patients who had "become very unwell" after injecting high doses of retatrutide

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leptin (red, 2 mg/kg body weight) or vehicle (black) injection on cumulative ad libitum food intake in 12- to 18-week-old male WT ( C ) and Bbs5 / ( D ) mice over 24 hours ( n = 9 per group)