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Avoiding high-fat foods, which delay stomach emptying further, is one of the most effective strategies

Particularly, individuals on medications that lower blood sugar could face a heightened risk of hypoglycemia

The safety profile of retatrutide in individuals with T2DM was also favorable [103]

It also showed particular benefits for visceral fat reduction and liver fat clearance

Trial exclusion patterns Phase 2 and Phase 3 retatrutide trials commonly excluded participants with a history of pancreatitis, medullary thyroid carcinoma, multiple endocrine neoplasia syndrome type 2 (MEN 2), severe gastroparesis, recent major cardiovascular events, severe kidney impairment, type 1 diabetes (in the obesity studies), and pregnancy or breastfeeding

For these individuals, a modified approach may be appropriate