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1, Supplementary Notes 1, 2, Supplementary Figs

Deficiencies or mutations in SOD have been linked to various pathological conditions, including: As an endogenous antioxidant enzyme, SOD works in concert with other components of the body's antioxidant defense system to maintain redox homeostasis and protect cells from oxidative damage

Methionine specifically activates S-adenosylmethionine (SAMe), the universal methyl donor for hundreds of enzymatic reactions including those that regulate fat metabolism and neurotransmitter synthesis