Gastrointestinal dysfunction Some FIP presentations include GI involvement affecting nutrient absorption
The light modifier subunit GCLM is enzymatically inactive but plays an important regulatory function by lowering the Km of GCLC for glutamate and raising the Ki for GSH [7, 8]
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In type 2 diabetes and related states, this switch is broken: glucagon stays inappropriately high after meals, and the liver keeps producing glucose it does not need, worsening the postprandial spike
Vassalle C, Maltinti M, Sabatino L
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