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The study showed that lacking BTBD9 caused enhanced activity and excitability in these dopaminergic neurons in the striatum

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Currently in clinical development by Eli Lilly, retatrutide earned the nickname triple G because it mimics the action of three key metabolic hormones: GLP-1, GIP, and glucagon

Glucagon Receptor Activation : Promotes energy expenditure and fat oxidation, potentially enhancing weight loss